RNA-seq of spinal cord from nerve-injured rats after spinal cord stimulation
نویسندگان
چکیده
منابع مشابه
Spinal Cord-Injured Rats
Opérant conditioning of the spinal stretch reflex or its electrical analog, the H-reflex, is a new model for exploring the mechanisms of long-term supraspinal control over spinal cord function. Primates and rats can gradually increase (HRup conditioning mode) or decrease (HRdown conditioning mode) the H-reflex when reward is based on H-reflex amplitude. An earlier study indicated that HRdown co...
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Background—We studied the role of the central nervous system, neural feedback from contracting skeletal muscles, and sympathetic activity to the heart in the control of heart rate and blood pressure during 2 levels of dynamic exercise. Methods and Results—Spinal cord–injured individuals (SCI) with (paraplegia, n 4) or without (tetraplegia, n 6) sympathetic innervation to the heart performed ele...
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After spinal cord injury (SCI), the neurogenic bladder is observed to develop asynchronous bladder and external urethral sphincter (EUS) contractions in a condition known as detrusor-sphincter dyssnergia (DSD). Activation of the EUS spinal controlling center located at the upper lumbar spinal cord may contribute to reduce EUS dyssynergic contractions and decrease urethral resistance during void...
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Five warfare spinal cord injured patients with intractable constipation are described. Treatment with cisapride (4 x 10 mg daily) was undertaken. The agent cisapride significantly reduced the oral-anal transit time from 25.2 days to 14.4 days. It also improved other subjective complaints of these patients markedly. No side effects were seen during the trial.
متن کاملRetraining the injured spinal cord.
The present review presents a series of concepts that may be useful in developing rehabilitative strategies to enhance recovery of posture and locomotion following spinal cord injury. First, the loss of supraspinal input results in a marked change in the functional efficacy of the remaining synapses and neurons of intraspinal and peripheral afferent (dorsal root ganglion) origin. Second, follow...
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ژورنال
عنوان ژورنال: Molecular Pain
سال: 2018
ISSN: 1744-8069,1744-8069
DOI: 10.1177/1744806918817429